Signals of diseases such as gut microbiota imbalance, constipation, Irritable Bowel Syndrome (IBS), and gastroenteritis can lead to increased flatulence. 

Imbalances in gut microbiota can cause excessive gas production, while constipation can lead to the accumulation of waste and toxic gases. IBS presents symptoms like diarrhea, abdominal pain, and bloating. Gastroenteritis and poor gastric motility can also contribute to excess gas production. 

Additionally, hormonal changes, such as menopause or imbalances, can affect gut function and increase flatulence. Understanding these signals can help manage symptoms with mindset and lifestyle adjustments.